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DateLine Sunday, 27 April 2008

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Rats and bandicoot

plague could cause death:

Leptospirosis epidemic on the rise-don’t delay to seek medical care and adhere to preventive measures...

A plague of death due to Leptospirosis, a high risk zoonotic disease which mimics symptoms of serious viral fever similar to Dengue and Chickungunya has been reported from around the country causing 41 deaths up to April 11, Dr Navaratnasingam Janakan, Consultant Epideiologist, Epidemiology Unit of the Ministry of Healthcare and Nutrition told the Sunday Observer. Death due to the epidemic is on the increase because of delay in care seeking and failure to adhere to preventive measures. There is no vaccine to prevent Leptospirosis.

In 2007, the total number of Leptospirosis cases notified were 2195 with 34 deaths reported but this year up to April 11 the total number of cases notified has been 1147 and 41 deaths; an alarming increase causing much concern to health authorities. The highest number of reported cases have been from the Matale, Colombo, Kalutara, Matara, Gampaha and Galle districts.

A good number of cases were also reported in the Ratnapura, Hambantota, Moneragala and Anuradhapura areas as well, Dr Janakan said. ‘Leptospirosis is an infectious disease caused by bacteria leptospires and is more common in tropical countries.

Leptospires are naturally seen in the kidneys of rodents, certain mammals and livestock, canines and wild mammals in particular; a disease transmitted from animals to humans which was earlier identified as an occupational hazard affecting farmers especially during the paddy harvesting season, gem miners, sewage workers and those who engage in work in marshy land in particular.

However, the change in weather patterns, high humidity and periodic heavy rainfall has intensified outbreaks of Leptospirosis in the recent past. Usually, the peaks of incidence are the two monsoon periods’, Dr Janakan explained.

‘The bacteria leptospires is very virulent in rodents especially rats and bandicoots when they are displaced from their burrows and drains are contaminated due to floods.

These animals are said to continuously excrete leptospires with their urine although they do not suffer from the disease and exposure to leptospire contaminated environment which enters the body through abraded or traumatized skin, nasal, oral or eye mucous membranes leads to infection and causes Leptospirosis’, Dr Janakan further explained.

Leptospirosis may present a wide variety of clinical manifestations and mimic diseases such as dengue fever, influenza, meningitis and Jaundice posing a high risk as the incubation period is between 1-2 weeks.

The common symptoms are that the patient begins to develop high fever, redness of eyes and very severe muscular tenderness in the calf muscles notably in the lumbar region and some times due to incorrect diagnosis and the delay in proper care seeking could lead to death.

Death in such instances is often a result of complications which occur as a result of seeking proper care which in turn results in renal failure, miocarditis and bleeding in some organs especially the brain and the lungs.

‘Diagnosis of Leptospirosis should be considered in any patient presenting an abrupt onset of fever, chills, conjunctival suffusion, headache or muscle tenderness. If any doctor suspects that a patient could be having Leptospirosis he/she should refer the patient to the districts Epidemiology Unit as confirmatory diagnosis tests are not freely available.

Confirmatory diagnosis tests are available at the MRI, the Medical Faculty and some of the Private sector hospitals and these tests become positive only after the second week.

Even simple urine full report (albumin+) and white blood cells/ differential count (Polymorpholeucocytosis) would help the clinicians to make a probable diagnosis and decide if hospitalization is necessary.

Patients especially in high risk areas should give the doctor the history of the environment they are exposed to when seeking treatment.

Leptospirosis is a potentially serious but treatable disease and it has to be administered with the most effective antibiotics at the earliest. Doxycycline can be administered to people who are at very high risk’, Dr Janakan went on to explain.


How can you prevent Leptospirosis ?

Preventive measures must be based on knowledge of the high risk groups and the local epidemiological factors.

Raising awareness about the disease is a very important factor. Health care providers can play an important role by educating the public on how to recognize and treat the disease at the earliest. If you are or know of anyone involved in occupations such as farming, mining, cleaning drains and canals Dr Jankan’s advise is to inform the area MOH or PHI .


The following specific measures can help prevent Leptospirosis:

* Removal of rubbish and keeping areas around human habitation clean to control rodents.

* Keep animals away from gardens, playgrounds, sandboxes and other places where children play.

* Wear appropriate protective clothing, knee-high boots and gloves and cover all wounds with waterproof dressing *Use boiled water (chlorination is seldom useful as virulent organisms withstand up to 4 ppm; filtered water is also not safe)

* Avoid walking in flooded water

* Doxycycline has been reported to give some protection against infection and disease.


Highest number of cases of Leptospirosis reported from January -April 11, 2008

Matale 173

Colombo 137

Kalutara 135

Matara 123

Gampaha 106

Galle 115

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